NIH R01 · 2025
The promotion of parental behavior by the neurosteroid allopregnanediol
Summary Around 15% of women suffer from postpartum depression, which negatively impacts their motivation to care for their infants. Beyond postpartum depression, more than 600,000 children suffer from parental abuse or neglect (largely by parents themselves) in the United States, every year. Given how important parental care is to child development, it is thus critical to understand what shapes the motivation to care for young. Yet, the molecular and cellular mechanisms that contribute to interindividual differences in parental care are largely unknown. Here, we propose to characterize the mechanisms of action of the neurosteroid Allodiol, which promotes parental behavior in mice and is…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.