Benavente-Perez Lab

State College of Optometry

BIOLOGY

New York · United States

NIH-funded
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NIH R01 · 2025

Myopia and Glaucoma, Linked via Mechanotransduction Mechanisms Affecting the Ganglion Cell Complex

Project Summary/Abstract Public perception of myopia as a simple inconvenience masks its sight-threatening consequences. Even moderate levels of myopia predispose an individual to glaucoma at rates equal to a hypertensive's risk for cardiovascular disease. Yet, we lack specific diagnostic markers to identify glaucoma in myopic patients. In fact, myopic eyes can exhibit anatomical changes difficult to distinguish from glaucoma. This is alarming because half the world population is predicted to be myopic in 30 years, which will increase significantly the global prevalence of myopic glaucoma and associated visual impairment. Glaucoma is a complex neuropathy that preferentially affects the…

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