NIH R01 · 2025
Molecular mechanisms controlling tooth development
PROJECT SUMMARY Genetic diseases such as tooth agenesis, dentinogenesis imperfecta, infectious diseases such as caries or fractures represent common public health problems that affect up to 30-40% of the population worldwide and impose significant burdens on patients (Centers for Diseases Control and Prevention, 2019). The estimated direct costs of dental diseases amounted to $356.80 billion, totaling worldwide costs due to dental diseases of $544.41 billion in 2015. Given the unabated rise of dental diseases prevalence in the general population, it can only be expected that the number and cost will intensify in the future. As tooth regeneration remains elusive, restoring function and…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.