Becker-Dreps Lab

Univ of North Carolina Chapel Hill

FAMILY MEDICINE

Chapel Hill · United States

NIH-funded
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Research focus

NIH R01 · 2025

The INICIO-Guatemala Study: Improving Neurodevelopment with an Intestinal Health and Caregivers’ Intervention in the Occidente, Guatemala

ABSTRACT Child neurodevelopment (ND) is significantly impacted by nutrition in early life, a time of rapid growth and intricate development of the neurological system. In low resource settings, we now know that meeting nutrient recommendations alone is not enough to support optimal child growth and ND—a key driver of malnutrition and poor ND is environmental enteric dysfunction (EED), a subclinical intestinal condition of chronic inflammation and increased permeability. Therefore, to reduce the burden of poor ND, novel nutritional interventions are needed that incorporate this new understanding of intestinal health. Rice bran is a food with known prebiotic properties, important nutrients…

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