NIH R01 · 2024
Abstract: Phantom sound perception (tinnitus) arises from aberrant central auditory pathways. Subjective tinnitus is typically caused by hearing loss. Auditory cortex (AC) in tinnitus animal models exhibits increased spontaneous neural firing and synchrony. Another subset of tinnitus exists whereby patients (80%) can manipulate pitch, tone and/or volume of tinnitus with head and neck/jaw movements. Termed somatic or somatosensory tinnitus (ST), this modulable form of phantom sound perception is associated with cortical & subcortical plasticity. Somatosensory/trigeminal neural inputs to auditory brainstem and cortex likely underlie ST etiology & maintenance. Thus, two forms of subjective…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.