Basu Lab

Research focus

NIH R01 · 2024

Intergenerational impact of maternal trauma history on preschoolers' behavioral health outcomes: Assessing links with caregiving sensitivity and DNA methylation

PROJECT SUMMARY Background: This study seeks to better understand maternal trauma history as a driver of behavior health problems in 4-year-old children. We will examine the impact of maternal trauma across four time periods 1) maternal experience of pre-pregnancy abuse in childhood (when mothers < 18 years), 2) maternal experience of pre-pregnancy of abuse in adulthood, 3) maternal experience of abuse during pregnancy, and 4) maternal report of postnatal abuse (after childbirth to time of assessment) on their children’s behavioral problems (internalizing and externalizing behaviors). Using a lifecourse theory approach within an intergenerational context, we will test three models to…

From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.