Aydogan Lab

Case Western Reserve University

RADIATION-DIAGNOSTIC/ONCOLOGY

Cleveland · United States

NIH-funded
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NIH R01 · 2024

PSMA-targeted AuNPs for MR guided radiotherapy and radiosensitization

Clinical radiation therapy is a noninvasive means to mitigate cancer progression, which is prescribed for more than 50% of prostate cancer patients. Development of radiation technology, such as utilizing intensity- modulated radiotherapy (IMRT) to deliver highly conformal radiation dose distributions and image-guided radiotherapy (IGRT) to account for daily changes in target anatomy and positioning, allows unprecedented levels of accuracy and therapy outcome. The prostate is surrounded by many nerves and muscle fibers controlling different excretory and erectile functions that are difficult but necessary to avoid, it still remains a challenge to precisely deliver radiation doses to prostate…

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