NIH R01 · 2025
Revealing Cilia Function in the Human Fallopian Tubes
SUMMARY The overall objective of this study is to advance our understanding of the role motile cilia play in the fallopian tubes (FTs) and to develop an endoscopic imaging system for in vivo clinical investigation of motile cilia function in FT pathologies. The FTs transport oocytes, sperm, embryos, and provide the environment for the complex and highly regulated process of fertilization and preimplantation development. Motile cilia, dynamic hair-like structures that cover the luminal epithelium of the FTs, are known to play an essential role in reproduction, and impaired cilia motility is associated with fertility disorders in women and reproductive pathologies, including endometriosis.…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.