NIH R01 · 2024
Respiration and fitness in Bacteroides
PROJECT SUMMARY/ABSTRACT Bacteroidales is the most abundant order of bacteria in the human gut, yet we still know little about energy generating processes of these bacteria and how these systems support their fitness in the gut and affect host processes. We have demonstrated that Bacteroides have a complex respiratory chain that provides substantial energy during both anaerobic and nanaerobic growth. Our preliminary results reveal new and unexpected complexities of the respiratory pathway, new terminal electron acceptors that we predict contribute to bacterial and host fitness, and differences between Bacteroides species that likely impact microbiota composition. These important features…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.