Barnhart Lab

University of Pennsylvania

OBSTETRICS & GYNECOLOGY

Philadelphia · United States

NIH-funded
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NIH R01 · 2024

Clinical utility of novel biomarkers for prediction of early pregnancy failure

Abstract: The diagnosis and management for women who are at risk for ectopic pregnancy (EP) and spontaneous abortion (SAB), has not changed substantially in decades. While ultrasound can diagnose a significant portion of women at presentation, because of its limited accuracy in abnormal and early gestation, a large number of women need serial tests and procedures to determine the final location and viability of an early pregnancy. Misdiagnosis and iatrogenic complications during this time are still too common. This conundrum results in great stress and uncertainty for women undergoing clinical care and their health care teams. To date, we have demonstrated (and validated) that multiplexed…

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