Barnea Lab

Brown University

NEUROSCIENCES

Providence · United States

NIH-funded
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NIH R01 · 2024

Sensorimotor Transformations for Controlling Heading Direction in the Insect Central Complex

Survival of an organism relies on its ability to navigate through a complex environment. During navigation, the nervous system integrates spatial information from a wide variety of sensory modalities into a stable heading direction. In insects, such as the fruit fly Drosophila melanogaster, this process takes place in the central complex, a series of neuropil structures in the brain. A hallmark of the central complex is its columnar organization, in which neuronal activity appears as stable bumps that correlate with changes in the organism’s heading direction. The Drosophila central complex has been the subject of extensive anatomical and functional characterization, which has revealed how…

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