NIH R01 · 2024
Epigenetic Risk Factors for AD Age at Onset and Health Disparities: HABLE Epigenetics Study
The long-term goal of this research is to examine the link between DNA methylation patterns and presence and progression of Alzheimer’s disease (AD) among Mexican Americans (MA) and non-Hispanic whites (NHW). Here we will address the aims of PAR-19-070 (Research on Current Topics in Alzheimer's Disease and Its Related Dementias) – NOT-AG-18-047 – by leveraging the ongoing HABLE cohort (R01AG054073) to identify the epigenetic factors associated with presence and progression of AD among MAs and NHWs. In our prior work and recent HABLE data, we examined DNA methylation patterns among n= 90 age, gender and diagnosis-matched participants leveraging the HABLE Biorepository (MCI n=45, controls…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.