Bale Lab

University of Colorado Denver

PSYCHIATRY

Aurora · United States

NIH-funded
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Research focus

NIH R01 · 2025

Extracellular vesicles as biomarkers of trauma exposure and PTSD risk

Exposure to interpersonal violence (IPV) is associated with long-term negative mental health consequences, including an increased risk for posttraumatic stress disorder (PTSD), especially in women. The specific developmental timing of IPV is likely to play a significant role in disease outcomes where trauma experienced in late adolescence increases PTSD risk by 3-fold. However, little is known as to timing effects of IPV and PTSD risk related to sensitive periods of brain development and maturation. Our previous studies examined IPV experienced during specific developmental windows on health outcomes in a predominantly Black cohort of adult women. Our results revealed that…

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