NIH R01 · 2024
Diffuse Optics for Pediatric Hydrocephalus Management
ABSTRACT Hydrocephalus is a disorder of cerebral spinal fluid (CSF) physiology that results in progressive expansion of cerebral ventricles and elevated intracranial pressure (ICP). It affects 1-2 of every 1000 live births, making it the most common disease treated by pediatric neurosurgeons in the US. The usual treatment is neurosurgical shunt placement to divert CSF and relieve elevated ICP. Decision-making about when and if to intervene is mostly based on imaging evidence of enlarged ventricular size and clinical judgement. Ventricular size, however, is a suboptimal surrogate of elevated ICP and ischemia. Indeed, roughly 15% of patients experiencing elevated ICP do not have CT imaging…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.