NIH R01 · 2024
Mechanism of Meissner corpuscle function
Somatosensation is essential for everyday life. Many vertebrates, including humans, use the sense of touch to navigate in the environment, manipulate tools and objects, find food and perform various mechanical tasks. Key to this ability are somatosensory corpuscles located in the skin. In this proposal, we focus on Meissner corpuscles, which are essential for performing fine tactile tasks due to their ability to detect transient mechanical stimuli. Despite their importance for somatosensation, the mechanism of Meissner corpuscle function is unknown. Meissner corpuscles are located in the skin of many vertebrates, and consist of lamellar cells in contact with a neuronal mechanoreceptor. The…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.