Babb Lab

UT Southwestern Medical Center

INTERNAL MEDICINE/MEDICINE

Dallas · United States

NIH-funded
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Research focus

NIH R01 · 2025

Respiratory Effects of Obesity in Children: Longitudinal Consequences after 6 Years of Aging

Modified Project Summary/Abstract Section SUMMARY: Childhood obesity is one of the most common pediatric chronic diseases in the US. We have shown (HL136643) that over one year, children with obesity (CWO) can add four times as much fat weight as children without obesity (CWOO). However, it is unknown if this rate of increase in fat weight continues into adolescence, and whether respiratory function, exercise tolerance, or dyspnea on exertion (DOE) are progressively worsened by increasing obesity. Furthermore, there could be a sex difference in the effects of obesity, given the different growth characteristics for boys and girls. The overall objective of this proposal is to investigate the…

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