NIH R01 · 2025
Mechanism of F-18-fluorodeoxyglucarate accrual in myocardial injury
PROJECT SUMMARY Each year millions of individuals suffer from heart ailments such as myocardial infarction (MI), myocarditis, cardiomyopathies, etc. that lead to heart failure. Most heart failures are due to the loss of conductivity and contractility secondary to fibrosis that develops as a common response to these cardiac conditions. Early localization of myocardial fibrosis and its resolution is critical to address functional deficit in the failing heart as some types of cardiac fibrosis can be reversed by timely treatment before changes become irreversible. Current diagnostic methods to localize cardiac fibrosis are limited to either myocardial biopsy (invasive, risky, and prone to…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.