NIH R01 · 2025
Modeling and Interacting with the Visible Molecular Cell
PROJECT SUMMARY Integrative structural modeling of entire cells is a grand challenge actively being addressed by the structural biology community. The complexity and heterogeneity of structural models of entire cells poses several distinct challenges that are testing the current limits of technology and understanding. To tackle these challenges, we are developing the CellPACK Suite, a functional prototype of an entire integrative structural modeling pipeline. This pipeline allows users to gather and curate data from proteomics and structural databases, and to integrate this data into representative structural models that can be used for hypothesis generation and in-silico testing. Our goal…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.