NIH R01 · 2025
Peptidergic neuromodulation of microcircuits that control chemosensation-induced behaviors
PROJECT SUMMARY One of central functions of neuromodulation is to adjust the internal representations of sensory information ac- cording to the internal states of an individual. In particular, chemosensation can have dramatically different bio- logical meanings depending on the nutritional state. For instance, the smell of food not only informs an animal where the food is, but also how valuable it is. According to nutritional need, an animal uses the perceived value of the food as a context to adjust the level of competition with other conspecifics. While hunger is known to change the detection thresholds of olfactory and gustatory sensory neurons through neuromodulation, how the nervous…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.