Arnold Lab

University of California, San Francisco

OPHTHALMOLOGY

San Francisco · United States

NIH-funded
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NIH R01 · 2025

Enteric Pathogen Force of Infection among Children using Serology

Enteric pathogen infections are a leading cause of the global disease burden, with the largest burden among children in low-resource settings. Stool-based PCR methods have dramatically improved our ability to measure enteric infections, but the challenge of collecting stool and need for near-continuous monitoring to detect many globally important pathogens has thwarted broader use in large-scale surveillance. Large-scale, population- based surveys now regularly collect blood to monitor transmission and burden of diseases such as HIV, malaria and dengue. Broader testing of blood collected in such surveys with multiplex assays represents a new opportunity to measure enteric pathogen…

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