NIH R01 · 2024
Real-time in vivo proton range verification in proton therapy with thallium bromide detectors
Summary Radiotherapy using protons is an attractive option as it has the potential to better preserve healthy tissue compared to radiation with photons or electrons, and because trial outcomes indicate it can replace surgery for radical cancer treatments as well. Proton therapy makes use of the finite range of heavy charged particles with an intensity maximum at the end of their path (Bragg peak) followed by a sharp fall-off of the dose. However, predicting the proton range based on computed tomography (CT) scans carries an estimation uncertainty. For treatments with proximal critical organs and limited accessibility (head and neck), high heterogeneities (lung), or significant breath motion…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.