Ansell Lab

Pennsylvania State University, the

PSYCHOLOGY

University Park · United States

NIH-funded
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Research focus

NIH R01 · 2024

Neurobehavioral Effects of Frequent Co-use of Alcohol and Cannabis

Project Summary Simultaneous use of alcohol and marijuana/cannabis (SAM) leads to increased craving, use, and consequences compared to single use of either alcohol or cannabis. However, there is a dearth of knowledge regarding the neural, neuroendocrine, and behavioral differences in SAM users that increases risk for these negative outcomes. The current proposal aims to address this significant gap in knowledge by examining how stress related neural and neuroendocrine processes may differ in SAM users relative to single substance users or a control group. A sex-balanced sample of four hundred forty male and female individuals reporting SAM use, alcohol use only, cannabis use only, or…

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