NIH R01 · 2025
Neural Mechanisms of Vestibular Function
PROJECT SUMMARY We investigate an important function of the vestibular system, and its multisensory properties, in spatial navigation, specifically head direction (HD) cells. HD cells encode directional heading like a compass and these properties are generated through a ring attractor network that is defined by orienting landmarks and updated using self-motion velocity cues. The goal of this renewal application is to establish the principles and circuits linking vestibular signals to HD cells in the anterior thalamus, through three aims. In the first two aims we will thoroughly test theory-driven hypotheses about the self-motion signal that updates the ring attractor. We will disentangle…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.