Andres Lab

Arkansas Children's Hospital Res Inst

Little Rock · United States

NIH-funded
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NIH R01 · 2025

Perinatal PFAS Impact Children's Development: Examining the Roles of Placental Functional Multiomics and Protection by Maternal Exercise

PROJECT SUMMARY The perinatal period is well-recognized as a critical developmental window where organ systems are rapidly growing and tuning their functional programs. This is also a time when environmental exposures can have profound and long-term impacts on health if they disrupt these processes. Per- and polyfluoroalkyl substances (PFAS), a family of synthetic chemicals characterized by strong carbon-fluorine bonds, are of particular concern given their ubiquity in consumer products and their resistance to degradation. Exposures to PFAS prenatally are known to influence health outcomes, however the mechanisms that link prenatal PFAS to fetal and offspring outcomes are still unclear and…

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