NIH R01 · 2025
Advanced body composition imaging to improve outcomes in lung transplantation
PROJECT SUMMARY Median survival after lung transplantation (Tx) is only 6.7 years, compared to >11 years after other solid organ Tx. Obesity increases risk of death on the Tx waitlist, early severe lung injury (primary graft dysfunction, PGD), and death after lung Tx. We have repeatedly shown that measures of adipose distribution on computed tomography (CT) scan identify candidates at risk for pre-Tx, peri-operative, and post-Tx morbidity and mortality beyond body mass index (BMI). Measures of adipose distribution are routinely used to quantify risk in the general population. In fact after screening with BMI, obesity guidelines recommend further risk stratification by adipose distribution.…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.