Anastassiou Lab

Cedars-Sinai Medical Center

Los Angeles · United States

NIH-funded
Rate this labNo reviews yet — be the first.

Research focus

NIH R01 · 2025

Towards a biophysical model of human cortical neurophysiological signatures that incorporates cellular and cell type biophysics, transcriptomics, and morphology

Project Summary The past decade has seen an unprecedented accumulation of data at the single-cell level giving rise to unique, multimodal sets of gene expression patterns, morphologies, and electrophysiology characteristics. This high- resolution census of neuronal types in the brain constitutes an essential step towards a mechanistic understanding of circuits and brain computations. However, linking cellular identity and activity to circuits and neurophysiological signals remains daunting. The central goal of this proposal is to develop a set of publicly available computational models, tools and resources that allow testing mechanistic hypotheses about the role of different neuronal types…

From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.

Reviews

← All labs at Cedars-Sinai Medical Center