NIH R01 · 2025
AI-Assisted Microendoscopy for the Early Detection of Esophageal Cancer
Abstract: Esophageal cancer is the 6th most common cause of cancer-related mortality worldwide. While esophageal squamous cell neoplasia (ESCN) carries a significant global burden, those in certain underserved geographic regions (South America, eastern Africa, eastern Iran, northern China) have particularly high incidence and mortality rates due to lack of endoscopic screening capacity. While endoscopy with Lugol’s chromoendoscopy or “digital” chromoendoscopy has shown high sensitivity (>95%) for screening, specificity is poor (<60%) and false-positive results abound due to confounding inflammatory areas. As a result, standard of care endoscopy produces many unnecessary biopsies, increasing…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.