NIH R01 · 2024
Characterizing the evolution of Subjective Cognitive Decline in preclinical Alzheimer's disease
Project Summary As Alzheimer's disease (AD) treatment strategies increasingly focus on prevention at the preclinical stage, a corresponding effort to improve detection of early changes in cognitive function is urgently needed. Subjective Cognitive Decline (SCD) provides a unique opportunity to identify emerging cognitive symptoms from the person's own perspective that can complement neuropsychological assessment at the preclinical stage. Furthermore, SCD has direct applications for AD prevention trials seeking to demonstrate treatment effects that impact study participants' daily lives. We propose to recruit a new cohort of SCD individuals who report a concern for recent, persistent changes…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.