Amann Lab

Research focus

NIH R01 · 2024

Cardiovascular and neuromuscular issues in chronic pain

PROJECT SUMMARY / ABSTRACT Although chronic pain (CP) affects over 20% of the U.S. population, little is known about associated physiological consequences, which likely contribute to the patients’ functional limitations and high risk for cardiovascular disease. It is therefore the goal of this project to explore the impact of CP on cardiovascular function and to evaluate the potential and underlying mechanisms of an innovative pain management strategy to improve circulatory control in this vulnerable patient group. Two disease-related characteristics predispose CP patients to cardiovascular abnormalities during exercise. First, an enhanced responsiveness of sensory nerve endings and dorsal…

From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.