Alvarez Lab

Emory University

INTERNAL MEDICINE/MEDICINE

Atlanta · United States

NIH-funded
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NIH R01 · 2024

A Dietary Intervention to Improve Glucose Tolerance in Adults with Cystic Fibrosis

PROJECT SUMMARY/ABSTRACT Successes in therapies for individuals with cystic fibrosis (CF) have exponentially improved survival in this population. There is now a critical need for better understanding of how to promote optimal long-term health in this newly aging population, which is at high risk for development of glucose intolerance and CF-related diabetes (CFRD). CFRD is clinically and pathophysiologically distinct from type 1 and type 2 diabetes mellitus, and it drastically impairs quality of life and survival. Unfortunately, specific factors contributing to CFRD onset and progression remain unknown. Our preliminary data implicate diet as a precipitating factor in glucose intolerance in…

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