Alshareef Lab

Research focus

NIH R01 · 2025

Biomechanics of the Human Brain During High-Severity Impacts: A Multimodal Approach

Project Summary Traumatic brain injury (TBI) is a significant health care problem, affecting over 2.5 million people in the United States annually. Most cases are classified as mild or concussive TBI, caused by a rapid acceleration to the skull that may lead to short-term loss of consciousness and memory, as well as long-term disability. Prevention of TBI is therefore a critical consideration in contact sports, military operations, motor vehicle use and other activities. Accurate quantification of the locations, magnitudes, and orientations of brain deformation (strain) during TBI is a precursor to a better understanding of the onset and secondary cascades of injury. A key approach to…

From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.