NIH R01 · 2024
Absolute Brain Thermography using Multinuclear MRI
PROJECT SUMMARY Stroke is the leading cause of disability, the second leading cause of dementia, and the second leading cause of death worldwide, affecting nearly 800,000 patients per annum in the U.S. alone. Cerebrovascular ischemia is rapidly potentiated by rising body temperatures, occurring even with mild and sub-febrile hyperthermia. The potency of hyperthermic damage in ischemic brain arises due to impaired cooling in hypoperfused brain tissues. Consequently, localized brain hyperthermia can precede, and commonly exceeds, systemic temperature changes following ischemic injury, and is well-recognized as accelerating stroke progression and consumption of at-risk tissues. Despite severe…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.