Almaca Lab

Research focus

NIH R01 · 2024

Investigating the link between pericyte dysfunction and loss of glucose homeostasis in COVID-19

ABSTRACT The coronavirus disease 2019 (COVID-19) is a global healthcare crisis that in the USA kills about 1 person every minute. It is caused by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). While respiratory failure is still the most common cause of mortality in COVID-19 patients, serious manifestations are seen across multiple organs, including the pancreas. There is an intricate relationship between COVID-19 and pancreatic diseases such as pancreatitis and diabetes. Understanding the pathophysiological mechanisms that lead to pancreatic dysfunction and glucose intolerance in infected patients is of utmost importance. The pathogenesis of diabetes is intimately…

From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.