Allison Lab

University of California, San Diego

FAMILY MEDICINE

La Jolla · United States

NIH-funded
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Research focus

NIH R01 · 2024

Activity Levels, Myosteatosis and Insulin Resistance/Diabetes Mellitus

ABSTRACT Myosteatosis is a measure of body composition, which measures the presence and degree of fatty infiltration into the muscle compartment to include deposition around the muscle fibers/bundles, as well as into the muscle tissue itself. Our work on this measure of ectopic fat has shown myosteatosis to be strongly and significantly associated with measures of glucose regulation, independent of visceral and hepatic adiposity. Given the strong links between the glucose dysregulation (i.e. metabolic syndrome and/or diabetes mellitus) and arterial stiffness, as well as left ventricular structure and function, we believe the study of myosteatosis may be particularly relevant as a…

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