Allendorfer Lab

University of Alabama at Birmingham

NEUROLOGY

Birmingham · United States

NIH-funded
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NIH R01 · 2025

Exercise for Memory Rehabilitation in Epilepsy

Project Summary/Abstract Approximately 50% of the 3.4 million persons with epilepsy (PWE) in the U.S. have cognitive problems with memory deficits reported most commonly. Memory deficits negatively contribute to the personal and professional outcomes of PWE including quality of life. While cognitive rehabilitation programs have been utilized to help improve memory function in epilepsy, their efficacy remains unclear. Recently, memory improvements with formal exercise training have been shown in randomized controlled trials in healthy individuals, and in our pilot study in PWE who participated in supervised combined endurance and resistance training. Despite evidence of memory and other…

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