NIH R01 · 2025
Biomarker validation for intraductal papillary mucinous neoplasms of the pancreas
PROJECT SUMMARY/ABSTRACT: Intraductal papillary mucinous neoplasms (IPMN) of the pancreas are cystic tumors that represent a radiographically identifiable precursor lesion of pancreatic cancer. Currently, IPMN represent our best opportunity for intervention - and interception - prior to the development of an incurable cancer. The challenge however, is current laboratory, endoscopic, and imaging technologies are unable to distinguish between IPMN that is at low-risk (low-grade dysplasia) or at high-risk (high-grade dysplasia) of becoming an invasive cancer. In addition, our ability to improve diagnostic accuracy - particularly through biomarker development - has been difficult, as IPMN is…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.