NIH R01 · 2025
Contribution of CdiA to Pseudomonas aeruginosa pathobiology
Project Summary/Abstract Pseudomonas aeruginosa is a leading cause of healthcare-acquired infections worldwide. Many globally- distributed high-risk strains are emerging due to an increase in antibiotic resistance and acquisition of novel virulence traits. With diminishing treatment options for many of these severe P. aeruginosa infections, studies aimed at uncovering the virulence strategies used by these aggressive clinical strains should help to identify new targets for therapeutic intervention. Our research program aims to elucidate virulence strategies that enhance the pathogenicity of P. aeruginosa. We recently employed a comparative genomics approach to interrogate the accessory…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.