Allen Lab

Research focus

NIH R01 · 2024

Facilitating the Implementation of Population-wide Genomic Screening (FOCUS)

Population-wide genomic screening (PGS) for Hereditary Breast and Ovarian Cancer Syndrome, Lynch Syndrome, and Familial Hypercholesterolemia offers great promise in identifying the 1-2% of the population that unknowingly carries a pathogenic variant that puts them at elevated risk for serious, yet preventable disease. Rapidly decreasing sequencing costs, endorsement of PGS by national bodies, and attention to precision medicine applications have rapidly accelerated the spread of PGS programs. To date, no clear guidelines or implementation strategies exist to support the rapid growth of PGS. Contextual factors, including program-level procedures, organizational structure, and characteristics…

From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.