Allen Lab

Northwestern University at Chicago

RADIATION-DIAGNOSTIC/ONCOLOGY

Chicago · United States

NIH-funded
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NIH R01 · 2024

Linking in vivo hemodynamics with outcomes in Type B aortic dissection using 4D flow MRI

PROJECT SUMMARY/ABSTRACT Type B aortic dissection (TBAD) risk-stratification is increasingly relevant in the era of thoracic endovascular aortic repair (TEVAR), as outcomes and costs can differ significantly depending on treatment choice and timing. In addition to clinical and social/demographic risk factors, morphologic imaging biomarkers such as aorta diameter, entry tear size or locations, and false lumen (FL) thrombus have been used to predict which patients are at risk of adverse aorta-related outcomes (AARO). However, these morphologic parameters only indirectly reflect the underlying hemodynamic drivers (e.g. flow, stasis, and pressure) that lead to AARO. Our group has shown that 4D…

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