Allen Lab

Univ of Arkansas for Med Scis

PHARMACOLOGY

Little Rock · United States

NIH-funded
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Research focus

NIH R01 · 2024

MnBuOE as a Novel Chemosensitizer for Breast Cancer and Neuroprotector

Project Summary Background: The cognitive deficits observed after treatment with chemotherapeutic drugs are a significant clinical problem, with a rapidly increasing impact on the quality of life of millions of Americans. One and a half million people are diagnosed with cancer every year in the US, and more than 60% survive for 20 years or more. Cancer survivors have long reported cognitive dysfunction at various stages of the disease course with associated consequences upon well-being and functional independence. Several studies conducted over the past decade have indicated that cognitive impairment occurs long before cancer treatment begins and even before cancer diagnosis. Despite…

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