NIH R01 · 2024
Simple and rapid POC detection for fungemia
ABSTRACT Fungal species are among the most common causes of nosocomial bloodstream and invasive infections in immunocompromised hosts. Mortality from candidemia can be very high, ranging from 20-40%. Cryptococcus affects approximately 2-3% of solid organ transplant patients and Cryptococcus gattii has emerged as a new cause of pneumonia and disseminated fungal disease. The global emergence of virulent multidrug resistant species such as Candida auris, with a mortality reported to be as high as 68% is particularly worrisome. Culture- based tests to detect Candida infections are slow, relatively insensitive, and may have difficulty distinguishing between C. auris and other related Candida…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.