NIH R01 · 2025
CRCNS: Emergence of Coordinated Multi-Region Brain Activity Supporting Behavior
Changes in interactions between neurons enable diverse computations and flexible behaviors. Such changes can occur very rapidly by rerouting information flow through existing connections, or more slowly by updating connections. The proposed project will study how local and brain-wide dynamics arise during learning of goal-directed behaviors. Experiments will use novel ‘all-optical’ experimental techniques to causally map network interactions at cellular resolution in combination with data-constrained computational models, to follow the learning process in the living brain with unprecedented detail. The investigation will focus on learning mechanisms in several novel memory-guided behavioral…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.