NIH R01 · 2025
Psychopharmacological effects of cannabidiol on responses to stress and nicotine withdrawal
Summary Despite advances in tobacco smoking cessation interventions (pharmacological and behavioral), most smokers do not succeed at quitting, creating a major public health burden. Stress is one of the most commonly reported precipitants of tobacco craving and relapse. Tobacco withdrawal is associated with escalation of negative affect symptoms; our research has found multiple stress-related physiological and hormonal alterations during withdrawal that predict relapse. Modifying these stress-related biobehavioral changes may prove useful in reducing effects of stress. Cannabidiol (CBD) is a phytocannabinoid of cannabis with low abuse liability that has received increased attention in the…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.