Ajala Lab

Ge Medical Systems Information Technologies, Inc

Niskayuna · United States

NIH-funded
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NIH R01 · 2025

Functional Magnetic Resonance Imaging and Deep Learning to Improve Deep Brain Stimulation Therapy

PROJECT SUMMARY/ABSTRACT Successful treatment of Parkinson's disease (PD) using deep brain stimulation (DBS) therapy requires an optimal setting of stimulation parameters to correct brain function anomalies. The commonly employed DBS 1.0 electrodes have only four contact locations (with no stimulation directionality) that are used to electric pulses to a target volume of the brain. DBS 1.0 electrodes require the optimization of four stimulation parameters: signal frequency, voltage, pulse width, and contact location. In current standard-of-care optimization protocol, the DBS parameters are adjusted (via trial and error) until the physician determines an optimal set of parameters. This…

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