NIH R01 · 2025
Coronary Atherosclerotic Burden in AsA-NHPI: the Role of the Gut Microbiome
Cardiovascular disease (CVD) is the leading cause of death among Asian American, Native Hawaiian, and Pacific Islander (AsA-NHPI) adults, with rates varying across subgroups. However, the distribution of CVD risk factors in AsA-NHPI populations and how these factors influence CVD remain poorly characterized. Research addressing these gaps is needed to better understand CVD in AsA-NHPI populations. This study aims to investigate the relationship between the gut microbiome and coronary artery calcium (CAC)—a validated measure of current coronary atherosclerosis and a predictor of future cardiovascular events—beyond traditional risk factors. While animal models suggest a causal link between…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.