NIH R01 · 2024
Tissue Perfusion Pressure for Improved Management of Circulatory Shock
Circulatory shock is one of the most common reasons for admission to an intensive care unit (ICU) and results from inadequate blood pressure and blood flow to support organ function. Causes of circulatory shock include heart failure, sepsis, and hemorrhage. Prompt treatment is required to restore adequate blood pressure to prevent severe organ injury and death. Consensus guidelines for treatment of shock provide general targets for mean arterial pressure (MAP) that can be used to adjust medications, but optimal individual pressure goals for patients with various diseases and comorbidities remain uncertain. Prospective randomized clinical trials looking at different patient populations have…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.