NIH R01 · 2024
GABAergic Cells in the Periaqueductal Gray Region Control Food-Seeking
Project Summary/Abstract Abnormalities in feeding behaviors are a key symptom of several conditions, including binge-eating disorder, anorexia and obesity. In order to develop novel treatments, it is imperative to gain a deeper understanding of the circuits controlling adaptive feeding. Eating is affected by metabolic and hedonic features, and it consists of several actions, including exploratory food-seeking and consumption. Despite its central clinical and biological importance, networks controlling these behaviors are not well-understood. Prior data have indicated that activation of several GABAergic inputs to the midbrain lateral and ventrolateral periaqueductal gray (l/vlPAG) elicit…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.