NIH R01 · 2025
Long-term effects of electronic cigarettes on brain health
ABSTRACT Electronic cigarettes (e-cigs) are being touted as safer alternatives to traditional cigarettes, which have well- known harmful effects on the brain due to combustion-related inflammation and oxidative stress. Some smokers report using e-cigs to help quit smoking and switch to exclusive e-cig use. However, nicotine itself, as well as the other components of e-cig vapor, produce inflammation and oxidative stress, albeit to a lesser extent than traditional cigarettes. The effects of long-term e-cig use on the brain are poorly understood. Smoking cessation is associated with improvements in brain structure and function that correlate with quit duration, suggesting a recovery from the…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.