NIH R01 · 2024
Bridging Scales to Understand Endogenous Neuromodulation and its Regulation
Neuromodulatory nuclei detect and transform brain network activity into simpler signals, then send neurotransmitters back out to large-scale brain networks to change their function. Such nuclei are centrally implicated in mental disorders and adaptive resilience, and their regulation remains an untapped resource for interventions. The purpose of this grant is to understand how neuromodulatory nuclei detect and in turn influence distributed patterns of brain activity to impact behavior. To understand their regulation and effects on brain function, the investigative team has developed novel neuroimaging, behavioral, and analytic methods. These methods include: training participants to…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.