Abadi Lab

Duke University

RADIATION-DIAGNOSTIC/ONCOLOGY

Durham · United States

NIH-funded
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Research focus

NIH R01 · 2025

Accuracy and Precision in CT Quantification of COPD Through Virtual Imaging Trials

Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of death. Increasing in prevalence, COPD is a major burden to patients and providers. Computed tomography (CT) can provide valuable information about the structural and functional abnormalities of the disease as demonstrated in numerous studies where quantitative CT is deployed to characterize and evaluate the treatment. For instance, the COPDGene study has recently shown the substantial role of quantitative CT in the redefinition of COPD diagnosis, and in evaluating the progression of emphysema over time. However, these biomarkers vary across different scanners, settings, and patient attributes. There is a crucial need to…

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